Supports Glycemic Balance & Metabolic Response. This dietary supplement is Non-GMO, Gluten Free, Soy Free, and Vegan. Doctor's Best Benfotiamine features Benfotiamine, a fat-soluble form of Vitamin B1 that supports a balanced glycemic response and antioxidant defense. It helps maintain tissue health and contributes to overall well-being by supporting antioxidant function and a balanced glycemic & metabolic response already within the normal range. Benfotiamine is a derivative of thiamin, belonging to the family of compounds known as "allithiamines". Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin. Benfotiamine raises the blood level of thiamin pyrophosphate (TPP), the biologically active co-enzyme of thiamine, and stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways. Ingredients: Microcrystalline cellulose, modified cellulose (vegetarian capsule), silicon dioxide. Directions: Take 1 capsule daily, with or without food, or as recommended by a nutritionally-informed physician.