This 300ml refill can be used to refill Pet Remedy calming sprays and battery operated atomiser. The atomiser refill is a clinically proven, natural and water based formulation with low dosage valerian, vetiver, basil, and sage to helps calm your furry friend without sedating. The battery operated atomiser helps your animal become more attentive and responsive and is starts to help immediately by mimicking your furry friend's own natural calming mechanism. The atomiser refill lasts up to 8 weeks and is suitable for a small room (10m2 or 100sq ft). Pet Remedy works alongside the brain's natural messengers called neuro-transmitters, which work by telling the nerve receiving the message either to calm (via GABA pathway) or get 'fired up'. In times of stress or anxiety the nerves get over stimulated, which leads on to the many different signs of stress we see in our pets. The special Pet Remedy blend of essentials oils works alongside these natural relaxation pathways to help calm the nerves of anxious or stressed pets.