Colief Infant Drops - 7ml. Colief is safe to use with babies from birth, whether breast or formula-fed. Always follow the instructions to ensure Colief Infant Drops help your baby. For breastfed babies, add 4 drops to a few tablespoons of expressed milk and feed on a sterilised spoon. For infant formula, add 4 drops to warm formula, shake, and feed as normal. For ready-to-feed formula, add 4 drops to warm feed, shake, and feed. For formula made in advance, add 2 drops to warm formula, refrigerate for at least 4 hours, and warm before feeding. Colief is an enzyme destroyed by heat, working best in warm milk. Always follow formula manufacturer instructions. Do not add to milk that is too hot or cold. Stool patterns may change, resembling looser, more frequent stools of breastfed babies; reduce drops if this occurs. Seek medical advice for any health concerns.