TMG can be taken with NMN for optimal efficacy, providing the necessary methyl groups for NMN to be as efficient as possible. TMG supports normal methylation, a process essential for many cellular functions including lipid metabolism and liver detoxification, and correlates to a healthy cardiovascular system. Research shows healthy methylation is important in keeping DNA healthy in every cell and organ of the body, and by supporting healthy methylation, TMG also helps facilitate DNA repair. Studies show TMG lowers homocysteine levels due to donation of methyl groups. High homocysteine levels are correlated with an increased risk of heart disease, dementia, and stroke.