Active folate for mood, heart health, fetal development, and nerve support. Thorne's 5-MTHF Methyl Folate is an active, tissue-ready form of folate. This dietary supplement provides foundational support for mood, heart and vessels. It is gluten-free. 5-MTHF is a bioactive, methylated form of folate, an essential B vitamin that supports heart, brain, blood, and bone health and is suitable for individuals with MTHFR gene mutations. Suitable for vegetarians.