Denamarin provides high-level nutritional support for the liver due to its synergistic combination of S-adenosylmethionine (SAMe) and silybin. These enteric-coated tablets protect the active ingredients from oxidation. The product is available in different sizes tailored for cats, small dogs (up to 5kg), medium dogs (5-15kg), and large dogs (over 15kg). Administration instructions recommend an overnight fast or a minimum of 2 hours after feeding for optimal absorption. The tablet coating may appear beige. Each medium dog tablet contains SAMe 225mg and Silybin 24mg.